Eventos

Speaker: Dr. Francesc R. Garcia-Gonzalo

Group Leader –  Biochemistry Department-UAM School of Medicine, Autonomous University of Madrid (UAM), Spain.

Abstract

Primary cilia are microtubule protrusions of the plasma membrane that function as cell type-specific antennae in many of our tissues. These antennae must be tuned in order to perform their key signaling functions. Such tuning involves the correct ciliary targeting of proteins implicated in ciliary signaling. In this talk, we will focus on the ciliary targeting of INPP5E, a phosphoinositide phosphatase that controls ciliary composition and function, and whose mutations cause diseases known as ciliopathies.