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25 març 2022 @ 10:00 - 12:00

Mapping the structure of the extracellular matrix and engineering matrixbased disease models

Understanding disease necessitates a precise representation of the extracellular matrix (ECM), a vast, intricate structure made of ~1300 interwoven proteins and glycans supporting all organs and acting as a master cell regulator. In spite of its importance, there are no high-resolution maps of ECM topography.

I will present methods to isolate ECM from mammalian organs and generate a precise, quantitative, three-dimensional representation of the ECM in human organs during health and incurable conditions. Further development of these methods uses ECM scaffolds to engineer experimental models that recreate cell niches associated to advanced disease, aiming to break down the rules of their assembly.

Mostra els detalls

Data:
25 març 2022
Hora:
10:00 - 12:00
Lloc web:
https://ibecbarcelona.eu/event/ibec-seminar-alejandro-mayorca/

Organitzador

IBEC – Institut de Bioenginyeria de Catalunya

Recinte

Edifici Torres R+D+I, Torre I Planta 11
C/ Baldiri Reixac 4-8
Barcelona, Barcelona 08028 Espanya
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